An Overview on Gastroretentive Drug Delivery System (GRDDS)

Authors

  • Gaurav Sharma Himachal Institute of Pharmacy, Paonta Sahib, Himachal Pradesh, India
  • Ujjwal Nautiyal Himachal Institute of Pharmacy, Paonta Sahib, Himachal Pradesh, India
  • Sayeed Ahmad Himachal Institute of Pharmacy, Paonta Sahib, Himachal Pradesh, India

Keywords:

Gastroretentive drug delivery system; floating system; swelling; Review.

Abstract

A Controlled release dosage forms have been extensively used to improve therapy with several important drugs. However, the development processes are faced with several physiological difficulties such as the inability to restrain and localize the system within the desired region of the gastrointestinal tract and the highly variable nature of the gastric emptying process. This variability may lead to unpredictable bioavailability and times to achieve peak plasma levels. The present review addresses briefly about the classification, formulation consideration for GRDDS, factors controlling gastric retention, merits, demerits and applications of gastroretentive drug delivery systems.

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Published

2019-06-30

How to Cite

Sharma, G., Nautiyal, U., & Ahmad, S. (2019). An Overview on Gastroretentive Drug Delivery System (GRDDS). International Journal of Health and Biological Sciences, 2(2), 01–08. Retrieved from https://ijhbs.com/index.php/ijhbs/article/view/15

Issue

Vol. 2 No. 2 (2019): International Journal of Health and Biological Sciences

Section

Articles

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Author(s) hold the copyright and retain publishing rights without restrictions. 

 This work is licensed under a Creative Commons Attribution 4.0 International License.