Enzymatic Trans-esterification of Phospholipids to Aceto-phospholipid: A Good Surface Active Emulsifier and the Role of Phospholipid in Drug Delivery System

Abstract

Aceto-phospholipids were prepared enzymatically by incorporating the acetate group at sn-1 or sn-2 position with out acetylating the amine group of phospholipids. There are a sharp change in surface properties after acetylation. At the same time the emulsifying properties of aceto-phospholipids is also remarkable than original soy phospholipids. We have got the separate droplet size distribution pattern of water in oil type of emulsion in presence of different aceto phospholipids compare to original soy phospholipids. The emulsification properties of newly prepared aceto-phospholipids were explained from the HLB values. The biological activities of the aceto-phospholipid were also highlighted here using some reported articles.